Frequently Asked Questions

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Everythings Up offers a variety of health services including regular check-ups, lab tests, vaccinations, and consultations with our experienced doctors.

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Testosterone is a hormone primarily produced in the testes in men and in smaller amounts in the ovaries and adrenal glands in women. It plays a key role in the development of male reproductive tissues (testes and prostate), secondary sexual characteristics (muscle mass, body hair, and deep voice), and maintaining bone density, fat distribution, red blood cell production, and libido.

 Symptoms of Low T include:

• Fatigue
• Decreased libido
• Erectile dysfunction
• Loss of muscle mass
• Increased body fat
• Depression and mood changes
• Difficulty concentrating

Low testosterone is diagnosed through a blood test that measures total testosterone levels, typically conducted in the morning when levels are highest. Free testosterone and other hormones like LH (luteinizing hormone) and FSH (follicle-stimulating hormone) may also be tested to determine the cause.

 TRT can be administered in several forms:

• Injections – Intramuscular or subcutaneous
• Gels – Absorbed through the skin
• Patches – Applied to the skin daily
• Pellets – Implanted under the skin
• Oral tablets – Less commonly used due to liver strain

Benefits of TRT include:

• Increased muscle mass and      strength
• Improved libido and sexual      function
• Enhanced mood and mental clarity
• Increased energy levels
• Improved bone density

Potential risks and side effects include:

• Increased red blood cell count (polycythemia)
• Acne and oily skin
• Breast enlargement (gynecomastia)
• Testicular shrinkage
• Infertility
• Increased risk of heart disease and stroke (in some cases)

TRT can suppress natural testosterone production and sperm production, leading to reduced fertility. This occurs because exogenous testosterone decreases luteinizing hormone (LH) and follicle-stimulating hormone (FSH) production, which are necessary for sperm production.

Monitoring includes:

• Regular blood tests for testosterone levels
• Monitoring hematocrit and hemoglobin to avoid polycythemia
• Prostate-specific antigen (PSA) testing for prostate health
• Evaluation of symptoms and overall health status

Lifestyle factors include:

• Regular exercise, particularly strength training
• Adequate sleep (7–8 hours per night)
• Balanced diet rich in healthy fats, lean protein, and nutrients
• Reducing stress through mindfulness or relaxation techniques 
• Maintaining a healthy body weight 

Testosterone levels naturally decline by about 1% per year after the age of 30. This decline can lead to symptoms of low testosterone, such as reduced muscle mass, fatigue, and sexual dysfunction.

Low testosterone levels have been linked to depression, anxiety, and mood swings. TRT can improve mood, reduce irritability, and enhance mental clarity, but excessive testosterone can also increase aggression and impulsivity.

Excess body fat, especially visceral fat, increases the conversion of testosterone to estrogen through the enzyme aromatase, which can lower overall testosterone levels. Weight loss and a healthy diet can help restore balance.

Testosterone supports red blood cell production and vascular health, but high levels can increase the risk of blood clots, heart attack, and stroke due to increased hematocrit and blood viscosity.

Testosterone can improve sleep quality by reducing symptoms of sleep apnea and increasing deep sleep cycles. However, excessively high testosterone levels may disrupt sleep patterns or worsen sleep apnea.

Chronic stress increases cortisol levels, which can inhibit testosterone production. Reducing stress through exercise, relaxation, and mindfulness can help maintain balanced testosterone levels.

The HPG axis regulates testosterone production:

• The hypothalamus releases gonadotropin-releasing hormone (GnRH).
• GnRH stimulates the pituitary to release luteinizing hormone (LH).
• LH stimulates the testes to produce testosterone.
• TRT can suppress this natural feedback loop, reducing endogenous testosterone production.

Contraindications include:

• Prostate cancer or elevated PSA levels
• Breast cancer
• Severe untreated sleep apnea
• High red blood cell count (polycythemia)
• Uncontrolled heart disease

Excessive alcohol consumption can lower testosterone levels by:

• Increasing estrogen conversion
• Damaging Leydig cells in the testes
• Reducing sleep quality, which impacts testosterone production

Total testosterone includes both bound and free testosterone. Free testosterone is the biologically active form that can bind to androgen receptors and produce effects. Low free testosterone with normal total testosterone may still indicate a deficiency.

Testosterone is considered a performance-enhancing substance and is banned in most competitive sports. Athletes with diagnosed hypogonadism may receive a therapeutic use exemption (TUE), but misuse for performance enhancement can lead to penalties and disqualification.